PFAS 101: Everything You Need to Know About Toxic ‘Forever Chemicals’


The following is a definitive guide to PFAS chemicals, starting with their history, what has made them so beneficial to manufacturing, their impact on the environment, and why we must find alternatives. We also go in-depth on the methods available to remove them from soil and water, as well as regulations that are being made this very moment to control their use and limit their negative impacts.

Introduction to PFAS

What is PFAS?

PFAS, or per- and polyfluoroalkyl substances, are a large group of man-made chemicals used in various industrial and consumer applications since the 1940s. They are characterized by a carbon chain backbone, bonding carbon atoms to fluorine atoms, creating a solid and stable chemical structure. This unique structure gives PFAS remarkable properties—such as water and oil resistance, along with heat and chemical stability.

Chemical structure of Perfluorooctanoic Acid, a type of PFAS

PFAS chemicals can be found in various products, including nonstick cookware, stain-resistant carpets, water-resistant clothing, food packaging, and firefighting foams. Due to their persistence in the environment and potential health concerns, PFAS chemicals have gained increasing attention from researchers, regulatory agencies, and the public.

History of PFAS Development

An abbreviated history of PFAS development and awareness of the environmental impacts.

The history of PFAS development dates back to the 1930s and 1940s when researchers accidentally discovered the unique properties of these chemicals. The timeline of PFAS development can be summarized as follows:

  1. 1938: Dr. Roy J. Plunkett, a chemist working for DuPont, discovered polytetrafluoroethylene (PTFE), the first PFAS compound while trying to create a new refrigerant. PTFE exhibited remarkable heat resistance, nonstick properties, and chemical stability. It was later commercialized under the brand name Teflon.
  2. The late 1940s-1950s: DuPont and 3M began the large-scale production and commercialization of PFAS chemicals, which were used in various applications, such as nonstick cookware, electrical insulation, and stain-resistant coatings.
  3. The 1960s-1970s: The use of PFAS chemicals expanded to include water-resistant textiles, firefighting foams, and food packaging materials.
  4. The 2000s: Growing concerns about the persistence, bioaccumulation, and potential health effects of PFAS chemicals led to increased research and regulatory scrutiny. In 2000, 3M announced the phase-out of perfluorooctanesulfonic acid (PFOS) production, one of the most widely used PFAS chemicals.
  5. 2006: The US Environmental Protection Agency (EPA) launched the PFOA Stewardship Program, which aimed to reduce emissions and product content of perfluorooctanoic acid (PFOA) and related chemicals by 95% by 2010 and eliminate them by 2015. Major manufacturers, including DuPont and 3M, participated in this voluntary program.
  6. The 2010s: Many countries started implementing stricter regulations on PFAS chemicals, limiting their use and release into the environment. Manufacturers began developing and promoting alternative, less harmful PFAS compounds and non-PFAS alternatives.

The history of PFAS development is marked by significant scientific advancements and commercial success. However, as our understanding of these chemicals’ environmental and health effects has grown, there has been a shift toward more stringent regulations and the development of safer alternatives.

Types of PFAS

While there are over 4,000 known PFAS compounds, some of the most well-known and studied types include:

  1. Perfluorooctanoic acid (PFOA): Also known as C8, PFOA was widely used in the production of nonstick cookware, stain-resistant textiles, and other consumer products. Due to its persistence in the environment and potential health risks, its production and use have been reduced significantly in recent years.
  2. Perfluorooctanesulfonic acid (PFOS): PFOS was used in various applications, such as firefighting foams, stain repellents, and electroplating. It has been phased out by major manufacturers due to environmental and health concerns.
  3. Perfluorobutanesulfonic acid (PFBS): PFBS is a shorter-chain PFAS compound used as a replacement for PFOS in some applications. It is considered less bioaccumulative and persistent than PFOS, but its long-term health and environmental impacts are still under investigation.
  4. GenX: GenX is a trade name for a group of PFAS chemicals used as a replacement for PFOA in the production of nonstick coatings and other applications. It is considered to have a lower environmental impact than PFOA, but its long-term health effects are not yet fully understood.
  5. Perfluoroalkyl carboxylic acids (PFCAs): PFCAs are a group of PFAS chemicals with a carboxylic acid functional group. They include compounds like PFOA and have been used in various industrial and consumer applications.
  6. Perfluoroalkyl sulfonic acids (PFSAs): PFSAs are another group of PFAS chemicals with a functional sulfonic acid group. They include compounds like PFOS and have been used in applications such as firefighting foams and stain repellents.

These are just a few examples of the many types of PFAS chemicals. Researchers are constantly working to better understand their properties, environmental impacts, and potential health risks to inform regulations and develop safer alternatives.

How PFAS are used

Consumer Products Containing PFAS

Sources of PFAS include nonstick cookware, dental floss, cosmetics, and firefighting foam.
Sources of PFAS include nonstick cookware, dental floss, cosmetics, and firefighting foam.

PFAS chemicals have been used in various consumer products due to their unique properties, such as resistance to water, oil, and heat, and their chemical stability. Here are 12 examples of consumer products that may contain PFAS:

  1. Nonstick cookware: PFAS chemicals, such as PTFE (Teflon), have been used to create nonstick surfaces in cookware like frying pans, pots, and baking sheets.
  2. Stain-resistant carpets and upholstery: PFAS chemicals can be found in stain-resistant treatments applied to carpets, upholstery, and other textiles to help resist spills and stains.
  3. Water-resistant clothing: Outdoor and sports apparel, such as jackets, pants, and shoes, may contain PFAS chemicals to provide water and stain resistance.
  4. Food packaging: Some fast-food wrappers, microwave popcorn bags, and other grease-resistant food packaging materials may contain PFAS to prevent oil and grease from soaking through.
  5. Dental floss: Some dental floss products have been coated with PFAS chemicals to reduce friction and make it easier to slide between teeth.
  6. Cosmetics: PFAS chemicals can be found in certain cosmetics, including foundation, mascara, and eye shadow, for their water- and oil-resistant properties.
  7. Cleaning products: Some cleaning products, such as stain removers and carpet cleaners, may contain PFAS chemicals to enhance their cleaning performance.
  8. Paints and varnishes: PFAS chemicals can be used in certain paints, varnishes, and sealants to provide water and stain resistance, as well as improved durability.
  9. Ski wax: PFAS chemicals have been used in ski wax formulations to reduce friction and improve glide on snow.
  10. Insecticides: Some insecticides may contain PFAS chemicals to improve their effectiveness and increase their persistence in the environment.
  11. Firefighting foams: PFAS chemicals, particularly PFOS, have been used in firefighting foams, known as aqueous film-forming foams (AFFF), to help extinguish petroleum-based fires.
  12. Electronics: PFAS chemicals can be used in electronic components, such as semiconductors, wire insulation, and cooling systems, for their heat resistance and electrical insulation properties.

Note that regulations and voluntary industry efforts have led to the reduction or elimination of PFAS chemicals in some of these products. However, it is essential to remain informed and cautious about the presence of PFAS in consumer goods.

Industrial Applications for PFAS

PFAS chemicals have been widely used in various industrial applications due to their unique properties, including resistance to water, oil, and heat and chemical stability. Some of the notable industrial applications for PFAS include:

  1. Fluoropolymer production: PFAS chemicals, such as PTFE (Teflon) and other fluoropolymers, are used in various industries for their nonstick, heat-resistant, and chemically stable properties. Typical applications include electrical insulation, seals and gaskets, hoses, and tubing.
  2. Surface treatments and coatings: PFAS chemicals are used to create water-, oil-, and stain-resistant coatings for textiles, carpets, upholstery, leather, and paper products.
  3. Metal plating and finishing: PFAS chemicals, particularly PFOS, have been used as surfactants, mist suppressants, and leveling agents in the electroplating and metal finishing industries.
  4. Semiconductor manufacturing: PFAS chemicals are used in the electronics industry for processes such as etching, cleaning, and photoresist stripping due to their chemical stability and heat and electrical conductivity resistance.
  5. Firefighting foams: Aqueous film-forming foams (AFFF) containing PFAS chemicals, primarily PFOS, have been widely used to extinguish petroleum-based fires in various settings, including airports, refineries, and military installations.
  6. Pesticides and herbicides: PFAS chemicals can be used as adjuvants, dispersants, or active ingredients in particular pesticide and herbicide formulations to enhance their effectiveness, solubility, and persistence.
  7. Aviation and aerospace: PFAS chemicals are used in the aviation and aerospace industries for their heat resistance and electrical insulation properties, including hydraulic fluid, wire insulation, and gaskets.
  8. Automotive industry: PFAS chemicals are used in various automotive applications, such as fuel systems, transmission seals, hoses, and tubing, due to their heat resistance, chemical stability, and low friction properties.
  9. Construction materials: PFAS chemicals can be added to some construction materials like sealants, adhesives, and waterproofing membranes to provide water and stain resistance, as well as improved durability.
  10. Oil and gas industry: PFAS chemicals are employed in the oil and gas industry as surfactants, corrosion inhibitors, and lubricants in drilling fluids, hydraulic fracturing fluids, and other applications.

While PFAS chemicals have provided numerous benefits in various industries, their persistence in the environment and potential health risks have led to increased scrutiny, regulatory measures, and efforts to find safer alternatives.

Health and environmental impacts of PFAS

Human health risks

woman standing indoors
Studies have suggested associations between PFAS exposure and adverse health issues.

PFAS chemicals have been the subject of growing concern due to their persistence in the environment, bioaccumulation potential, and potential human health risks. While research on the health effects of PFAS is ongoing, several studies have suggested associations between PFAS exposure and various adverse health outcomes. Some of the human health risks that have been linked to PFAS exposure include:

  1. Immune system effects: PFAS exposure has been associated with a weakened immune response, which may increase the risk of infections and reduce the effectiveness of vaccines.
  2. Reproductive and developmental effects: Some studies have shown that exposure to PFAS chemicals may lead to adverse pregnancy outcomes, such as low birth weight, preterm birth, and developmental delays.
  3. Hormone disruption: PFAS chemicals can interfere with the endocrine system, leading to hormone imbalances and potential impacts on growth, metabolism, and reproduction.
  4. Liver damage: High levels of PFAS exposure have been linked to liver damage and increased liver enzyme levels, which could lead to liver disease.
  5. Kidney function: Some studies have reported an association between PFAS exposure and reduced kidney function, leading to an increased risk of chronic kidney disease.
  6. Cholesterol levels: PFAS exposure has been associated with increased levels of total cholesterol and low-density lipoprotein (LDL) cholesterol, which may increase the risk of cardiovascular disease.
  7. Cancer: Some PFAS chemicals, such as PFOA and PFOS, have been classified as possibly carcinogenic to humans by the International Agency for Research on Cancer (IARC). Studies have reported associations between PFAS exposure and an increased risk of certain types of cancer, such as kidney and testicular cancer.
  8. Obesity and diabetes: Emerging evidence suggests a link between PFAS exposure and an increased risk of obesity and type 2 diabetes, potentially due to their endocrine-disrupting properties.

It is important to note that while these associations have been reported in scientific studies, more research is needed to fully understand the causal relationships and the underlying mechanisms. Additionally, individual susceptibility to PFAS-related health risks may vary depending on factors such as genetics, the specific PFAS chemicals involved, the level and duration of exposure, and other environmental factors.

The C8 Health Project

One influential study on the impact of PFAS on human health is the “C8 Health Project,” which was conducted as part of a settlement following a class-action lawsuit against DuPont. The lawsuit was related to the contamination of drinking water with perfluorooctanoic acid (PFOA) from a DuPont manufacturing plant in Parkersburg, West Virginia. The study is notable for its large sample size and comprehensive evaluation of potential health effects related to PFOA exposure.

“The C8 Health Project was an unprecedented effort to assess the potential health impacts of PFAS exposure in a large community. Our findings contributed to a better understanding of the potential risks associated with these chemicals and have informed subsequent research and regulatory actions. The project not only helped the affected communities but also set a precedent for the importance of large-scale human health studies in addressing environmental contaminants like PFAS.”

The C8 Health Project involved the collection of health data from nearly 70,000 individuals who had been exposed to PFOA-contaminated drinking water. Participants completed a detailed health questionnaire and provided blood samples for analysis. An independent science panel, known as the C8 Science Panel, was established to evaluate the data and determine whether any links existed between PFOA exposure and human health effects.

After years of research, the C8 Science Panel concluded that there was a “probable link” between PFOA exposure and six health outcomes:

  1. High cholesterol (specifically elevated levels of total and LDL cholesterol)
  2. Ulcerative colitis (a form of inflammatory bowel disease)
  3. Pregnancy-induced hypertension (high blood pressure during pregnancy, including preeclampsia)
  4. Thyroid disease
  5. Testicular cancer
  6. Kidney cancer

After years of research, the C8 Science Panel concluded that there was a “probable link” between PFOA exposure and six health outcomes

These findings contributed to the growing body of evidence regarding the potential human health risks associated with PFAS exposure. The C8 Health Project and the conclusions of the C8 Science Panel have significantly impacted regulatory actions, public awareness, and ongoing research related to PFAS chemicals.

It is important to note that while the C8 Health Project focused on PFOA exposure, other PFAS chemicals may have different health effects. More research is needed to understand the full range of potential risks associated with exposure to various PFAS compounds.

National Health and Nutrition Examination Survey (NHANES)

PFOS exposure assessment was conducted as part of the National Health and Nutrition Examination Survey (NHANES) in the United States. The NHANES is a program run by the Centers for Disease Control and Prevention (CDC) that collects data on the health and nutritional status of the U.S. population.

In a study published in 2007, the CDC analyzed blood samples from a representative sample of the U.S. population for the presence of PFOA, PFOS, and other PFAS chemicals. The study aimed to establish a baseline for PFAS exposure in the general population and identify potential associations between PFAS exposure and various health outcomes.

“The NHANES study has been instrumental in providing a snapshot of PFAS exposure in the U.S. population. By measuring PFAS levels in blood samples from a diverse group of individuals, we have been able to gain insights into the prevalence and trends of these chemicals in our communities. The valuable data generated by NHANES not only helps us understand the extent of PFAS exposure but also guides public health policy and regulatory actions to protect human health from potential risks associated with these persistent chemicals.”

The results of the NHANES study showed that PFAS chemicals were detectable in the blood of most of the U.S. population, indicating widespread exposure to these compounds. Additionally, the study found associations between PFAS exposure and specific health outcomes, such as:

  1. Increased cholesterol levels: The study found a positive association between PFAS exposure (particularly PFOA and PFOS) and elevated total and LDL cholesterol levels.
  2. Thyroid hormone disruption: The study reported associations between higher PFAS exposure and changes in thyroid hormone levels, suggesting a potential impact on thyroid function.
  3. Liver enzyme levels: The study found positive associations between PFAS exposure and increased levels of certain liver enzymes, which could indicate liver damage.
  4. Reduced kidney function: The study reported associations between higher PFAS exposure and decreased kidney function, as measured by the estimated glomerular filtration rate (eGFR).

It is important to note that while the NHANES study identified associations between PFAS exposure and various health outcomes, it was not designed to establish causality or determine the specific mechanisms underlying these associations. Nonetheless, the NHANES study has been influential in raising awareness of PFAS exposure in the general population and contributing to the growing body of evidence regarding the potential human health risks associated with PFAS chemicals.

Environmental consequences

PFAS in the environment
Environmental consequences of PFAS contamination are of significant concern.

The environmental consequences of PFAS contamination are of significant concern due to their persistence, mobility, and potential for bioaccumulation. Some of the key environmental consequences of PFAS contamination include the following:

  1. Persistence in the environment: PFAS chemicals are highly resistant to degradation due to the strength of the carbon-fluorine bonds. As a result, they can persist in the environment for many years, making them challenging to remediate.
  2. Contamination of water sources: PFAS chemicals are highly mobile in water, which means they can easily spread and contaminate groundwater, surface water, and drinking water sources. Contaminated water can affect both human health and the health of aquatic ecosystems.
  3. Bioaccumulation in organisms: PFAS chemicals can accumulate in the tissues of living organisms, including fish, birds, and mammals, through the food chain. High levels of PFAS accumulation can lead to toxic effects in these organisms, potentially causing population declines and disruptions in the ecosystem.
  4. Impacts on wildlife: PFAS chemicals have been shown to have adverse effects on the health of various wildlife species, including liver damage, reproductive and developmental issues, hormonal imbalances, and immune system dysfunction.
  5. Transport to remote locations: PFAS chemicals can be transported over long distances through air and water currents, leading to contamination in remote areas far from their original sources. This can result in the exposure of wildlife and human populations that may not be directly linked to the primary sources of PFAS pollution.
  6. Challenges in remediation: Due to their persistence and mobility, PFAS chemicals are difficult to remove from the environment. Remediation methods, such as activated carbon filtration, ion exchange, and reverse osmosis, can sometimes be effective but are often expensive and resource-intensive.

The environmental consequences of PFAS contamination have prompted regulatory actions, increased public awareness, and ongoing research to understand the full extent of their environmental impacts and develop safer alternatives.

The Environmental Working Group (EWG) Study

One noteworthy study on PFAS and the environment is a research project conducted by the Environmental Working Group (EWG) and Northeastern University, which created an interactive map of PFAS contamination sites in the United States. This comprehensive project aimed to provide a better understanding of the extent of PFAS contamination in the country and identify potential sources of pollution.

Interactive map of PFAS contamination
Interactive map of PFAS contamination

The study utilized data from multiple sources, including the U.S. Environmental Protection Agency (EPA), state environmental agencies, the Department of Defense, and peer-reviewed scientific studies. The researchers compiled and analyzed data on PFAS contamination in drinking water, groundwater, surface water, and other environmental media.

“The EWG’s groundbreaking work in mapping PFAS contamination sites across the United States has been a game-changer in raising public awareness about these persistent chemicals. Their comprehensive research has not only helped to identify communities at risk but also prompted a more proactive approach towards understanding and managing PFAS contamination. EWG’s efforts have been instrumental in driving policy changes and encouraging the development of more stringent regulations to protect public health and the environment from the potential impacts of PFAS.”

Key findings from the study include:

  1. Widespread contamination: The study identified over 2,000 PFAS contamination sites across 49 states in the U.S., indicating that PFAS pollution is a widespread issue affecting communities nationwide.
  2. Drinking water contamination: The researchers found that millions of Americans were potentially exposed to PFAS-contaminated drinking water, with contamination levels sometimes exceeding the EPA’s health advisory levels for PFOA and PFOS.
  3. High-risk locations: The study identified several locations with an increased risk of PFAS contamination, including military installations, airports, industrial sites, and wastewater treatment plants. Firefighting foams used at military bases and airports were a significant source of PFAS pollution.
  4. Variability in state regulations: The researchers noted that state regulations for PFAS chemicals varied widely. Some states set more stringent standards for PFAS contamination in drinking water and the environment than others.
  5. Need for further research: The study highlighted the need for more research on the environmental and health impacts of PFAS chemicals and the development of effective remediation strategies and alternatives to PFAS-containing products.

The EWG and Northeastern University study has been instrumental in raising awareness of the extent of PFAS contamination in the U.S. and its potential impact on the environment and human health. It has also contributed to increased public pressure for more decisive regulatory actions and the development of safer alternatives to PFAS chemicals.

Regulatory framework

United States regulations

In March 2023, the Environmental Protection Agency (EPA) made a significant move to safeguard public health by proposing a national drinking water standard for six per- and polyfluoroalkyl substances (PFAS). This proposal is a crucial component of the Agency’s PFAS Strategic Roadmap, aiming to establish legally enforceable limits for these six PFAS compounds known to occur in drinking water. The EPA aims to set nationwide health-protective levels for these specific PFAS chemicals in drinking water by leveraging the latest scientific research and building on existing state efforts.

US President's PFAS Report
A 2023 report by the United States Joint Subcommittee on Environment, Innovation, and
Public Health on PFAS.

Additionally, in February 2023, the EPA announced the availability of $2 billion from President Biden’s Bipartisan Infrastructure Law to address emerging contaminants, including PFAS, in drinking water throughout the United States. Allocated to states and territories, this funding will be made available to communities as grants through the EPA’s Emerging Contaminants in Small or Disadvantaged Communities grant program. This substantial investment aims to ensure safe and clean water access in small, rural, and disadvantaged communities while supporting local economies.

Several U.S. states have developed their own regulations and guidelines for PFAS chemicals in drinking water, groundwater, and surface water. These regulations vary among states, with some establishing more stringent standards than the EPA’s health advisory levels:











New Hampshire

New Jersey

New York

North Carolina



Rhode Island




West Virginia

European Union regulations

The European Union (EU) has been actively working to regulate and control PFAS chemicals due to their persistence, the potential for bioaccumulation, and adverse effects on human health and the environment. The European Chemicals Agency (ECHA), along with other EU institutions and member states, is leading the efforts to manage PFAS chemicals in Europe. Some of the key regulatory actions and initiatives related to PFAS in the EU include:

  1. REACH Regulation: The Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH) regulation is the primary EU legislation governing chemicals. Under REACH, several PFAS substances have been identified as Substances of Very High Concern (SVHCs) due to their persistent, bioaccumulative, and toxic (PBT) properties or their very persistent and very bioaccumulative (vPvB) nature. Listing these substances as SVHCs initiates a process that can lead to further regulatory actions, such as restrictions or authorizations.
  2. PFAS Restrictions: ECHA, in collaboration with the European Commission and EU member states, is working on a broad restriction proposal for PFAS chemicals. This proposal aims to limit the use of PFAS in various products, such as textiles, food packaging, and firefighting foams, to reduce their release into the environment and minimize human exposure.
  3. Monitoring and Data Collection: ECHA, along with the European Food Safety Authority (EFSA), the European Commission, and other EU agencies, collects and evaluates data on the occurrence and effects of PFAS chemicals in the environment and human populations. This information helps inform risk assessments, regulatory actions, and the development of safer alternatives to PFAS-containing products.
  4. International Cooperation: The EU actively participates in international efforts to address PFAS chemicals, such as the Stockholm Convention on Persistent Organic Pollutants (POPs). Several PFAS substances, including PFOA and its related compounds, have been added to the Stockholm Convention, which requires parties to take measures to eliminate or reduce the release of these chemicals.
  5. Supporting Research and Innovation: The EU funds research and innovation projects to understand the environmental and health impacts of PFAS chemicals, develop new analytical methods for their detection, and explore safer alternatives to PFAS-containing products.

Overall, the European Union is committed to protecting human health and the environment from the potential risks posed by PFAS chemicals. Through regulatory actions, data collection, international cooperation, and support for research and innovation, the EU aims to reduce PFAS exposure and promote the development of safer alternatives.

Global initiatives

International efforts to regulate PFAS include the Stockholm Convention on Persistent Organic Pollutants, which has listed PFOS and its derivatives as restricted substances. Additionally, the United Nations Environment Programme (UNEP) and the World Health Organization (WHO) are working on guidelines and recommendations for PFAS management.

PFAS detection and testing

Detecting and testing for PFAS chemicals in various environmental media, such as water, soil, and air, as well as in human blood samples, is a critical aspect of understanding their distribution, potential sources of contamination, and exposure risks. Analytical methods for PFAS detection have advanced significantly in recent years, allowing for more accurate and sensitive measurements of these chemicals.

Testing for PFAS chemicals in water, soil, and air is critical to understanding their distribution.

The most commonly used method for detecting PFAS compounds in environmental samples is liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). This technique involves separating the PFAS compounds in a sample using liquid chromatography and then analyzing their molecular composition and concentration with mass spectrometry. LC-MS/MS can detect a wide range of PFAS compounds at very low concentration levels, typically in the parts-per-trillion (ppt) range.

“Advancements in analytical techniques like LC-MS/MS have significantly improved our ability to measure these chemicals and inform decision-making processes related to their management.”

In addition to laboratory-based methods like LC-MS/MS, portable testing devices and field sampling techniques are being developed to facilitate on-site testing for PFAS compounds. These innovative approaches can reduce the time and costs associated with sample collection, transport, and analysis, thereby enhancing the capacity for monitoring and managing PFAS contamination.

It is crucial to regularly update and validate PFAS testing methods to ensure that they remain accurate, reliable, and capable of detecting emerging PFAS compounds. Ongoing research and development in this field will help to refine existing analytical techniques and create new methodologies for detecting PFAS, ultimately supporting more effective management strategies for these chemicals.

Remediation and mitigation strategies

Water treatment technologies

top view of concrete structures
In some cases, a combination of technologies may be employed to achieve the desired level of PFAS removal.

Various water treatment technologies have been developed and implemented to remove PFAS from contaminated water sources. Some of the most effective methods include:

  1. Granular Activated Carbon (GAC) filtration: GAC filtration uses activated carbon to adsorb PFAS compounds from the water. The porous structure of activated carbon provides a large surface area for the adsorption of PFAS, effectively trapping the contaminants as the water flows through the filter. GAC filtration is widely used due to its cost-effectiveness and ability to treat large volumes of water. However, the efficiency of GAC filtration can be influenced by the type of PFAS compound, the concentration of the contaminants, and the presence of other organic materials in the water.
  2. Ion Exchange (IX) resins: IX resins are synthetic polymers that can selectively remove specific ions, such as PFAS, from water. The resin beads have charged functional groups that bind to PFAS compounds, exchanging them for less harmful ions. IX resins can be highly effective in removing PFAS, but their performance can be influenced by water chemistry, competing ions, and targeted PFAS compound. Additionally, IX resins can have a higher capital cost than GAC filtration.
  3. Reverse Osmosis (RO): RO is a membrane-based technology that uses pressure to force water through a semi-permeable membrane, separating PFAS and other contaminants from the water. The process can effectively remove a wide range of PFAS compounds and other contaminants like salts, minerals, and organic molecules. However, RO systems can be expensive, require significant energy input, and produce a concentrated waste stream (brine) that requires proper disposal or further treatment.
  4. Advanced Oxidation Processes (AOPs): AOPs involve generating highly reactive chemical species, such as hydroxyl radicals, that can break down PFAS compounds into less harmful byproducts. Some AOPs include combining UV light with hydrogen peroxide (UV/H2O2) or ozone (O3) to generate these reactive species. AOPs can effectively degrade PFAS, but their efficiency depends on the specific PFAS compound, the concentration of the contaminants, and the water chemistry. Additionally, AOPs can be energy-intensive and may generate potentially harmful byproducts.

Each of these treatment technologies has its advantages and limitations, and the choice of the most appropriate method depends on factors such as the type and concentration of PFAS compounds present, the water chemistry, the scale of the treatment system, and the available budget. In some cases, a combination of technologies may be employed to achieve the desired level of PFAS removal.

Soil remediation

Closeup Photo of Sprout
Soil remediation is a crucial component of addressing PFAS contamination.

Soil remediation is a crucial component of addressing PFAS contamination, as PFAS chemicals can persist in the environment for extended periods, posing potential risks to human health and ecosystems. Several soil remediation technologies have been developed or adapted to treat PFAS-contaminated soil, aiming to remove or destroy the PFAS compounds. Here are some of the common approaches for soil remediation:

  1. Soil Excavation and Off-site Treatment: One approach for managing PFAS-contaminated soil is to excavate the affected material and transport it to an off-site facility for treatment or disposal. The treatment may involve techniques such as incineration, landfilling, or stabilization, depending on the nature of the contamination and the available resources.
  2. Soil Washing: Soil washing involves using water, solvents, or surfactants to extract PFAS compounds from the soil matrix. The contaminated water or solvent is then separated from the soil and treated using advanced filtration methods, such as granular activated carbon (GAC) or ion exchange, to remove the PFAS chemicals.
  3. Thermal Desorption: Thermal desorption is a process that involves heating the contaminated soil to volatilize the PFAS compounds, which are then captured and treated. High temperatures are required to break the strong carbon-fluorine bonds in PFAS chemicals, and the process must be carefully managed to avoid the formation of toxic by-products.
  4. Stabilization and Solidification: In some cases, it may be more feasible to immobilize PFAS compounds in the soil rather than attempting to remove them. Stabilization and solidification techniques involve using binding agents, such as cement or other materials, to encapsulate the PFAS chemicals and reduce their mobility and bioavailability.
  5. Phytoremediation: Phytoremediation is an emerging approach that uses plants to uptake and remove contaminants from the soil. While some studies have shown potential for phytoremediation of PFAS, further research is needed to understand the effectiveness of this technique and identify suitable plant species for PFAS removal.

It is important to note that selecting a suitable soil remediation technology depends on various factors, including the extent and nature of the contamination, the properties of the affected soil, and the availability of resources. Ongoing research and development efforts are crucial to improve existing remediation techniques and explore new, innovative methods for addressing PFAS contamination in soil.

Waste management

people sitting on gray concrete floor during daytime
Proper waste management procedures for PFAS are crucial to prevent further contamination.

Proper waste management procedures for PFAS-containing materials are crucial to prevent further contamination of the environment and protect human health. The following are some key steps and considerations in managing PFAS waste:

  1. Identification and characterization: Accurately identify and characterize the PFAS-containing waste, including the specific PFAS compounds present, their concentrations, and the physical and chemical properties of the waste. This information is essential for determining the appropriate treatment and disposal methods.
  2. Segregation and containment: Segregate PFAS-containing waste from other waste streams to prevent cross-contamination. Store the waste in appropriate containers that prevent leakage or migration of PFAS into the environment. Use secondary containment measures, such as lined storage areas or berms, to minimize the risk of accidental releases.
  3. Waste minimization: Implement waste minimization strategies to reduce the generation of PFAS-containing waste. This may include source reduction measures, such as using alternative materials or processes that do not involve PFAS and recycling or reusing materials whenever possible.
  4. Treatment: Treat PFAS-containing waste to remove, destroy, or immobilize the contaminants before disposal. Treatment options may include adsorption (e.g., using granular activated carbon or ion exchange resins), membrane filtration (e.g., reverse osmosis), thermal treatment (e.g., incineration), or other advanced technologies. The treatment method chosen depends on the specific PFAS compounds, their concentrations, and the waste characteristics.
  5. Disposal: Dispose of treated PFAS waste in a secure landfill or hazardous waste facility designed to prevent the migration of PFAS into the environment. In some cases, untreated PFAS waste may be landfilled if it meets the regulatory requirements for disposal and the landfill is designed to handle such waste. However, this approach may only transfer the risk to another location and should be considered carefully.
  6. Monitoring and reporting: Regularly monitor PFAS levels in the waste and surrounding environment to ensure that containment and treatment measures are effective. Report any incidents of PFAS releases or exceedances of regulatory limits to the appropriate authorities.
  7. Regulatory compliance: Adhere to local, regional, and national regulations governing the management of PFAS-containing waste. This may include requirements for waste characterization, storage, treatment, disposal, and reporting.
  8. Worker safety and training: Ensure that workers handling PFAS-containing waste are adequately trained in proper waste management procedures and provided with appropriate personal protective equipment (PPE) to minimize exposure risks.

Proper waste management procedures for PFAS-containing materials play a critical role in mitigating the environmental and human health risks associated with these persistent and potentially harmful compounds.

Future Outlook and Research

Emerging PFAS alternatives

Researchers are actively exploring alternatives to PFAS in various applications. Some potential alternatives include:

  1. Short-chain PFAS, which may have a lower potential for bioaccumulation and persistence
  2. Fluorine-free compounds, such as polyhydroxyalkanoates (PHA) or polysiloxanes, for certain applications
  3. Biomimetic materials inspired by nature, offering similar properties without the environmental risks

Public awareness and education

PFAS article on the WSJ
Public education, such as articles in the Wall Street Journal and other major news outlets, raise awareness of the need to mitigate PFAS risks.

Public education and awareness of PFAS chemicals are vital to addressing the challenges associated with their environmental presence and potential health risks. By informing the public about the sources, properties, and impacts of PFAS, individuals can make informed decisions to minimize their exposure and advocate for practical regulatory and management actions. The following points highlight the importance of public education and awareness of PFAS:

  1. Informed Decision-Making: Raising awareness about PFAS can empower individuals to make informed choices regarding their consumption habits and lifestyle. By understanding which products and materials may contain PFAS, people can make conscious decisions to reduce their exposure to these chemicals.
  2. Demand for Safer Alternatives: As the public becomes more informed about PFAS and their potential health and environmental impacts, there may be an increased demand for safer alternatives. This consumer-driven demand can encourage industries to invest in research and development of PFAS-free products, ultimately reducing the prevalence of these chemicals in the market.
  3. Policy Advocacy: Public awareness of PFAS can lead to greater demand for more stringent regulations and policies to protect human health and the environment. Informed citizens can advocate for stronger restrictions on PFAS production and use and more extensive monitoring and remediation efforts.
  4. Community Engagement: Educating the public about PFAS can lead to increased community engagement in addressing contamination issues. Armed with knowledge, community members can collaborate with local, state, and federal agencies to address PFAS contamination in their areas and promote responsible environmental stewardship.
  5. Supporting Research: Public awareness of PFAS can drive support for research initiatives focused on understanding these chemicals’ health and environmental impacts, as well as the development of remediation technologies and safer alternatives. Increased public interest in PFAS research can lead to more funding opportunities and collaborations between researchers, industries, and policymakers.

By raising awareness about these persistent chemicals, communities can come together to address the challenges posed by PFAS and work towards a healthier and more sustainable future.

Research gaps and priorities

Despite significant advancements in understanding PFAS chemicals, their properties, and their potential impacts, considerable research gaps still need to be addressed to better manage these compounds and their associated risks. Identifying and addressing these gaps is essential for developing more effective regulations, remediation strategies, and safer alternatives to PFAS-containing products.

Many short-chain and alternative PFAS compounds remain understudied.

One notable research gap lies in the characterization and assessment of the thousands of PFAS compounds that have not been thoroughly studied. While research has primarily focused on long-chain PFAS, such as PFOA and PFOS, many short-chain and alternative PFAS compounds remain understudied. Comprehensive toxicity data, environmental fate, and transport information for these lesser-known PFAS compounds are needed to inform appropriate risk assessment and management strategies. In addition, the development of analytical methods capable of detecting a broader range of PFAS chemicals at lower concentrations will be crucial in understanding the full extent of their presence in the environment and potential exposure pathways.

Another area requiring further research is the development of cost-effective and efficient remediation technologies for PFAS-contaminated media, including soil, groundwater, and surface water. While some treatment methods have shown promise, the unique chemical properties of PFAS, such as their persistence, mobility, and resistance to conventional remediation techniques, present significant challenges. Continued research and development efforts should focus on improving the efficacy and scalability of existing remediation technologies and exploring innovative approaches for PFAS removal or destruction. This includes evaluating the long-term effectiveness of in-situ treatment methods, optimizing the performance of adsorbent materials, and investigating novel strategies such as advanced oxidation processes or biological treatment.

Future priorities should include promoting safer alternatives to PFAS-containing products and materials.

Lastly, future priorities should include promoting safer alternatives to PFAS-containing products and materials. Research should be directed towards identifying and evaluating the safety and performance of alternative compounds and fostering the development of innovative PFAS-free technologies. Supporting the transition to safer alternatives will minimize the environmental release and human exposure to PFAS and help drive the market demand for more sustainable and responsible products. Collaboration between researchers, industries, and policymakers will be essential in accelerating the development and adoption of safer alternatives, ultimately reducing the reliance on PFAS-containing materials and mitigating their potential impacts on human health and the environment.

For More Information

EPA Website on PFAS
The EPA’s portal for PFAS information covers regulatory actions, research, and risk communication.

To further explore and understand the complexities of PFAS chemicals, their impacts on human health and the environment, and regulatory efforts to manage their use, consider the following resources and organizations:

  • U.S. Environmental Protection Agency (EPA) PFAS Action Plan: The EPA’s comprehensive resource for PFAS information covers regulatory actions, research, and risk communication.
  • European Chemicals Agency (ECHA)PFAS Information: ECHA’s PFAS information portal provides updates on regulatory actions, research, and guidance related to PFAS within the European Union.
  • Agency for Toxic Substances and Disease Registry (ATSDR)PFAS Toxicological Profiles: ATSDR offers detailed toxicological profiles for various PFAS, including health effects, exposure pathways, and regulatory guidelines.
  • Interstate Technology & Regulatory Council (ITRC)PFAS Fact Sheets: ITRC’s PFAS fact sheets cover various topics, including environmental fate, site characterization, treatment technologies, and risk communication.
  • Stockholm Convention on Persistent Organic PollutantsPFAS Information: The Stockholm Convention’s resource on PFAS provides information on the international regulation of persistent organic pollutants, including PFAS.

By exploring these resources and organizations, you can gain a deeper understanding of PFAS chemicals, their potential impacts, and the ongoing efforts to manage their use and mitigate their effects on human health and the environment.


PFAS are a large group of man-made chemicals with widespread use in consumer products, industrial applications, and firefighting foams. Their unique properties, such as resistance to heat, water, and oil, have led to their extensive use but also raised concerns about their persistence, bioaccumulation, and potential health and environmental impacts.

Efforts to understand and mitigate the risks associated with PFAS have included regulatory actions, the development of detection and testing methods, and the exploration of remediation and mitigation strategies. Future research priorities include understanding the impacts of less-studied PFAS compounds, identifying effective treatment technologies and remediation strategies, and investigating alternative PFAS compounds and their potential risks.

Collaboration among stakeholders and an integrative approach to PFAS risk assessment and management are essential for protecting human health and the environment. This includes monitoring and surveillance, transparent risk communication, and the development of effective policies and regulations based on scientific evidence and the precautionary principle.

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